Restrictions apply. Apidra Tools and Resources Take a more proactive approach to managing your blood sugar by accessing tools to help you stay in control. It is not known if APIDRA is safe or effective in children less than 4 years of age with type 1 diabetes or in children with type 2 diabetes. When used as a mealtime insulin, Apidra should be given within 15 minutes before or within 20 minutes after starting a meal. Apidra may be infused subcutaneously by external insulin infusion pumps.
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Restrictions apply. Apidra Tools and Resources Take a more proactive approach to managing your blood sugar by accessing tools to help you stay in control. It is not known if APIDRA is safe or effective in children less than 4 years of age with type 1 diabetes or in children with type 2 diabetes. When used as a mealtime insulin, Apidra should be given within 15 minutes before or within 20 minutes after starting a meal.
Apidra may be infused subcutaneously by external insulin infusion pumps. Do not share needles, insulin pens or syringes with others even if the needle is changed. Do NOT reuse needles. You may give other people a serious infection or get a serious infection from them.
Change rotate your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy pitted or thickened skin and localized cutaneous amyloidosis skin with lumps at the injection sites.
Do not use the same spot for each injection or inject where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged. Before starting Apidra, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.
Heart failure can occur if you are taking insulin together with pills called TZDs thiazolidinediones , even if you never had heart failure or other heart problems.
If you have heart failure, it may get worse while you take TZDs with Apidra. Your treatment with TZDs and Apidra may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have new or worsening symptoms, including: Shortness of breath Sudden weight gain Swelling of your ankles or feet Tell your doctor about all medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.
When used a mealtime insulin, Apidra should be taken within 15 minutes before a meal or within 20 minutes after starting a meal. Test your blood sugar levels as directed by your doctor when using Apidra. Do not change your dose or type of insulin without talking to your doctor.
Any change of insulin should be made cautiously and only under medical supervision. Check your insulin label to verify that you have the correct insulin before each injection. Use Apidra only if the solution is clear and colorless with no particles visible. While using Apidra, do not drive or operate heavy machinery until you know how Apidra affects you. Do not drink alcohol or use medicines that contain alcohol. Apidra may cause serious side effects that can lead to death, including: Low blood sugar hypoglycemia.
Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability or mood changes, hunger.
Serious allergic reactions. Get medical help right away if you have: a rash over your whole body, shortness of breath, trouble breathing, fast pulse, sweating or feeling faint Low potassium in your blood hypokalemia. Your doctor should monitor you for low blood potassium levels. Heart failure. Your doctor should monitor you closely while you are taking TZDs with Apidra. Get emergency medical help if you have: Trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, confusion.
The most common side effects of APIDRA include: low blood sugar hypoglycemia , weight gain, itching, rash, swelling, allergic reactions including injection site reactions, skin thickening or pits at the injection site lipodystrophy.
Please talk to your healthcare provider about proper injection techniques and follow instructions in the Instruction Leaflet that accompanies the pen. Important Safety Information for Apidra when used in a pump Replace the infusion sets reservoir, tubing, and catheter , and the Apidra in the reservoir at least every 48 hours and select a new infusion site.
Do not mix or dilute Apidra when used in the pump. Failure of your insulin pump or infusion set or degradation of the insulin in the pump can cause hyperglycemia and ketoacidosis. Always carry an alternate form of insulin administration in the case of pump failure. Click here for Full Prescribing Information for Apidra.
Click here for information on Sharps Medical Waste Disposal. The health information contained herein is provided for general educational purposes only. Only people without prescription medication insurance can apply for this offer. Void where prohibited by law. Offer is valid for one fill per month. When using the Insulins Valyou Savings Card, prices are guaranteed for 12 consecutive monthly fills.
The Insulins Valyou Savings Program applies to the cost of medication. There are other relevant costs associated with overall treatment. Important to note that if you have an Affordable Care Health Care Exchange plan, you may still be qualified to receive and use this savings card.
Upon registration, patients receive all program details. Sanofi US reserves the right to change the maximum cap amount, rescind, revoke or amend these programs without notice. All rights reserved. This site is intended for use by U. Sanofi US provides these links as a service to their website visitors and users; however, the company takes no responsibility for the information on any website but their own.
This site is intended for U. Healthcare Professionals only Do you wish to continue? Close Continue Important Safety Information Do not use Apidra if you have low blood sugar reaction or if you are allergic to insulin glulisine or any of the ingredients in Apidra.
Apidra® is a fast-acting and flexible mealtime insulin
There are risks to the mother and fetus associated with poorly controlled diabetes in pregnancy [see Clinical Considerations ]. Animal reproduction studies have been conducted with insulin glulisine in rats and rabbits using regular human insulin as a comparator. The effects did not differ from those observed with subcutaneous regular human insulin [see Data ]. The estimated background risk of miscarriage for the indicated population is unknown.
RECENT MAJOR CHANGES
Generalized allergy to insulin may cause whole body rash including pruritus , dyspnea, wheezing, hypotension, tachycardia, or diaphoresis. In controlled clinical trials up to 12 months duration, potential systemic allergic reactions were reported in 79 of patients 4. During these trials, treatment with Apidra was permanently discontinued in 1 of patients due to a potential systemic allergic reaction. Injection Site Reactions As with any insulin therapy, patients taking Apidra may experience redness, swelling, or itching at the site of injection. These minor reactions usually resolve in a few days to a few weeks, but in some occasions may require discontinuation of Apidra.
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